SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 1,2,5-TRIMETHYL-4-N-ARYLIMINO(AMINO)PIPERIDINES AND 4-(N-ARYL-N-ETHOXYCARBONYL)AMINOPIPERIDINES

Abstract

Some urethanes containing gamma-N-piperidyl substituents were synthesized fron the respective 4-N-arylimino(amino)piperidines and ethylchloroformate. The starting materials and the resultant ethyl-N-(1,2,5-trimethylpiperidyl-4)-N-aryl (hetaryl) carbamates were tested for bactericidal, fungicidal, and herbicidal activities which were shown to be related to the structure of the compounds in question. Some ethyl-N-(1,2,5-trimethylpiperidyl-4)-N-aryl-carbamates had action on the central nervous system. The compounds under study had no profound analgetic effect. The structure of the compounds was evidenced by spectral assays. The parameters for NMR- and mass-spectra are also outlined