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Human gut microbiota community structures in urban and rural populations in Russia
Authors
Abdulkhakov R.
Abdulkhakov S.
+29 more
Alexeev D.
Babenko V.
Belenikin M.
Cheremushkin S.
Efimov O.
Govorun V.
Grinevich V.
Karpova I.
Kostryukova E.
Kozlova I.
Kucheryavyy Y.
Larin A.
Livzan M.
Lyalyukova E.
Maev I.
Osipenko M.
Ospanova E.
Pavlenko A.
Popenko A.
Sagdeev R.
Sas E.
Selezneva O.
Semashko T.
Sergienko V.
Shcherbakov P.
Tkachev A.
Tsukanov V.
Tyakht A.
Vlassov V.
Publication date
29 February 2020
Publisher
Abstract
The microbial community of the human gut has a crucial role in sustaining host homeostasis. High-throughput DNA sequencing has delineated the structural and functional configurations of gut metagenomes in world populations. The microbiota of the Russian population is of particular interest to researchers, because Russia encompasses a uniquely wide range of environmental conditions and ethnogeographical cohorts. Here we conduct a shotgun metagenomic analysis of gut microbiota samples from 96 healthy Russian adult subjects, which reveals novel microbial community structures. The communities from several rural regions display similarities within each region and are dominated by the bacterial taxa associated with the healthy gut. Functional analysis shows that the metabolic pathways exhibiting differential abundance in the novel types are primarily associated with the trade-off between the Bacteroidetes and Firmicutes phyla. The specific signatures of the Russian gut microbiota are likely linked to the host diet, cultural habits and socioeconomic status. © 2013 Macmillan Publishers Limited. All rights reserved
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National Open Repository Aggregator (NORA)
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oai:rour.neicon.ru:rour/139304
Last time updated on 04/04/2020
National Open Repository Aggregator (NORA)
See this paper in CORE
Go to the repository landing page
Download from data provider
oai:rour.neicon.ru:rour/181245
Last time updated on 04/04/2020