ABSTRACT
Self-medication is a conscious effort to heal itself through the purchase of medicines needs directly to the
pharmacy. Self medication is a form of health behavior essentially a person's reaction to stimuli with illness and
disease, health care system, and the environment. As one of health supplier services, pharmacists play big roles
and responsibilities to self medication. These roles and responsibilities are based on pharmaceutical care
philosophy. The objective of this research is to reveal the interaction relationship between actors in social process
that cause self medication action to happen in Makassar. This research is a qualitative research, using 6
informants as data source which is collected using deep observation and interview. The result of this research
shows that communication between actors in self medication does not go smoothly, which is seen from many
drug misuse cases within Makassar society. From the observation of the informants, it was found a case of long
term misuses of deksamethason and cyproheptadine to raise appetite, prednisone dan phenylbutazone to cure
rheumatic as well as CTM, prednisone, and aminophylline to heal asthma disease in long term. The drug misuse
continues to be repeated due to the absence of public information available about the drugs they use, especially
to the side effects of these drugs when they are repeatedly used continuously in the long run. The implication of
these drug misuses can cause degenerative diseases along with a bunch of consequences. Based on this fact, it
can be concluded that the interaction between actors (patient-pharmacist) in self medication action within
Makassar society does not run well
