Suggested by conversations in 1991 (Mark~Krasnosel'ski\u{\i} and Aleksei~Pokrovski\u{\i}
with TIS), this paper generalizes earlier work (Krasnosel'ski\u{\i}-Pokrovski\u{\i} 1974) of theirs
by defining a setting of hybrid systems with isotone switching rules
for a partially ordered set of modes and then obtaining a periodicity
result in that context. An application is given to a partial
differential equation modeling calcium release and diffusion in
cardiac cells