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Acute transverse myelitis in children, literature review
Authors
A. Tabrizi
A. Tavasoli
Publication date
1 January 2011
Publisher
Abstract
Objective Acute transverse myelitis (ATM) is a rare inflammatory demyelinating disorder characterized by relatively acute onset of motor, sensory, and autonomic dysfunction. Children comprise 20 of total cases of ATM. In this review, we described the current literature on childhood ATM, focusing on the epidemiology, pathogenesis, clinical presentation, approach to diagnosis, differential diagnosis, treatment and outcome in the pediatric population. Materials &Methods We searched the related articles in electronic databases such as Scopus, EMBASE, Google Scholar, and PubMed. All study designs were included and the essential key words for searching were myelitis, acute transverse myelitis, childhood transverse myelitis, and acquired demyelinating syndromes. Results The related data focusing on the epidemiology, pathogenesis, clinical presentation, diagnostic approach and differential diagnosis, treatment and outcome of pediatric ATM were gathered and described. Conclusion ATM is a heterogeneous disorder in children with a broad spectrum of clinical presentation, etiology, and outcome. It may be the first presentation of relapsing acquired demyelinating syndromes and also must be distinguished from compressive and noninflamatory myelopathies. Correct diagnosis is crucial for treatment and prognosis. © 2018, Iranian Child Neurology Society. All rights reserved
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Cineca Institutional Research Information System
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oai:art.torvergata.it:2108/523...
Last time updated on 17/04/2020
ART
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oai:art.torvergata.it:2108/523...
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eprints Iran University of Medical Sciences
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oai:eprints.iums.ac.ir:6870
Last time updated on 10/10/2019