Micro-endodontic surgery attempt to minimize trauma and enhance esthetics soft tissue surgical results. Wound healing monitoring is performed for early identification of signs and symptoms related to surgical complications. The aim of this study was to compare surgical wound healing of soft tissue flap after using conventional scalpel and diode laser in micro-endodontic surgery. Methodology: This study was carried out as a randomized controlled clinical trial after taking approval of BAU institutional review board. Fourteen healthy patients were indicated for root end surgery; full mucoperiosteal tissue flap incision was done by using Bard-Parker Blades (Group I) and(Group II) Diode Laser with a wavelength of 940 nm set at a power of 1.5 W. Follow-up assessment scale was used at the day of surgery (baseline) and days1, 3, 7 and 30. After surgery to monitor the following clinical parameters including pain, swelling, bleeding and wound healing. Result: The clinical parameters investigated were statically analyzed and showed that there was no statistically significant difference between the laser and scalpel groups during all follow-up days (P \u3e 0.05). Conclusion: Both Diode Laser and Conventional Scalpel yield same effect on wound healing. Moreover, careful training in oral hygiene, combined with a valid surgical technique is essential to obtain the best result of soft tissue healing after micro-endodontic surgery
