Infrastructure projects are the backbone of the economy of the developed counties. Gaza Strip is suffering from non-prioritization of infrastructure project implementation. The objective of this paper was to identify the causes of nonprioritization infrastructure projects in the Gaza Strip. This paper considers the key causes of non-prioritizing infrastructure projects in Gaza Strip. Using an empirical questionnaire survey targeting groups consist of 5 ministries, 25 municipalities, 25 NGOs, international agencies and 59 consultancy firms working in Gaza Strip, respondents were invited to rate the level of importance of 52 causes have been finalized to be involved in this study from the literature. Results revealed that the most important causes are related to the project and its location, the surrounded political and economic environment, donors and project's owner. There is no consideration for local needs in the implementation of the infrastructure projects in the Gaza Strip and there are problems in the process of selecting infrastructure projects priorities by owners of these projects. Furthermore, several donors placing limitations on the type of infrastructure that it can support that related to their working area of aids and according to their political directions. Finally, the political and economic situation in Gaza Strip, and imposed borders blockade affects the decision-making process for the selection of the proposed projects. This paper will help the decision makers to consider the important aspects that should be considered when planning to infrastructure projects