The purpose of this study was to examine school culture as it mediates teachers’ job satisfaction and performance in secondary schools in Mbeya region. The study specifically focused on examining school culture and teacher motivation; assessing motivation and teacher job satisfaction as well as to determining teacher motivation and satisfaction to student learning. Correlation research design was used to get information from 220 teachers through questionnaires and interview. The study found that school culture such as rules and regulation, social interaction and relation had a lot to do with teacher motivation. The study also found a strong relation between teacher motivation and teacher job satisfaction. Further, the study found that when teacher were motivated and in high moral, they taught well and develop good relationship with student, a situation that also encouraged students to learn better and perform. The study suggests that there is the need for all school managers to improve school culture, by ensuring that the rules and regulations that are developed are fair to make it possible for both the teachers and students to adhere and interact amicably in everyday teaching and learning process
