Aims: Although the general public appears to have embraced the term 'video game addiction', the scientific debate as to whether 'gaming addiction' can actually be considered an addiction similar to substance addictions of DSM-IV is still unsettled. To date, research on gaming addiction has focused on problematic behavior from the gaming activity itself and there has been little empirical research related to pathological personality patterns that usually are associated with substance addictions. Therefore, the current study examined how excessive gaming and ‘problematic gaming behavior’ are related to personality patterns associated with addiction by means of the Minnesota Multiphasic Personality Inventory-2 MMPI-2). Design, setting, and participants: A large-scale survey study among 1,004 adolescent boys (age-range 11-18 years; M =14.18, SD=1.36; response rate 96.17%). Measurements: Problematic gaming behavior, physical game-related symptoms, gaming behavior and three MMPI-2 subscales measuring personality patterns usually associated with substance addiction (MAC-R, APS, AAS) were assessed. Findings: Results showed that problematic gaming and physical game-related symptoms were positively related to all three substance abuse subscales of the MMPI-2. Conclusions: Problematic gaming should be clearly distinguished from excessive gaming. In short, excessive gaming merely indicates enthusiasm for some although it may be psychopathological for others