The Monuments of the Artuqs period draw attention especially coming from the Middle Ages to the present day in Mardin where hosts different civilizations. Among these monuments, there are many similarities between the Zinciriye (Sultan İsa) Madrasah and the Kasimiye Madrasah build in Aqqoyunlu period, which was influenced by architectural of Zinciriye. This similarity gets noticed of some researchers, but the available data on comparisons are insufficient. While Kasimiye compared with madrasah of Zinciriye, which is about 100 years older than, the architectural style and lookout programs are identical. However, they are different as a plan. Whereas the masjids plans and the sliced pointed domes of both madrasahs are the same, the madrasah of Kasimiye is different with the onyx type dome, the monumental iwan rising along the two floors and the symmetrical madrasah room layouts. In the study monuments have been searched comparatively and new periodicals related to the originality of the monuments were reached, especially the republican period