The aim of this study was to examine the plasma Cu, Zn, and Mg levels in three different groups (control, hyperlipidemic, and hypercholesterolemic) and to determine any correlation between these parameters and the level of triglyceride (T.G), cholesterol (Chol), LDL, and HDL. For this purpose, serum Cu, Zn, and Mg levels were determined by atomic absorbtion spectrophotometry in three groups: Group I (n = 35 control, normal lipid profile); Group II (n = 36 hyperlipidemic); Group III (n = 15 familial hypercholesterolemia), and the results were statistically analyzed. The results and their statistical evaluation for the lipid and plasma Cu, Zn, and Mg levels were as follows: Only statistically significant differences were observed between Group I and Group II for T.G, Chol, LDL, and HDL, but no statistically significant differences were observed between the other groups and parameters. When associations between T.G, Chol, LDL, HDL, and plasma Cu, Zn, Mg were examined, significant correlations were observed between Cu and T.G (r = 0.356), Cu and Chol (r = 0.828), Cu and LDL (r = 0.806) in Group III; Zn and HDL (r = 0.543) in Group I, Zn and Chol (r = 0.378), Zn and LDL (r = 0.538) in Group III; Mg and T.G (r = 0.354), Mg and Chol (r = 0.444), Mg and LDL (r = 0.433), Mg and HDL (r = 0.375) in Group I
