Is there any difference in lateralization in epithelial ovarian cancer cases?

Abstract

WOS: 000449612300017Introduction: Whether there is a right or left lateralization difference in cancer involvement in double sided organs has become a topic of interest in recent years. In addition, the density of cancer metastasis to the right or left lymph nodes has become a subject of inquisition. Our aim in this study is to retrospectively investigate differences in right- or left-sided ovarian cancer incidence. Materials and methods: In the Gynaecological Oncology Clinic of Zonguldak Bulent Ecevit University, 96 patients with epithelial ovarian cancer who were followed up between 2008 and 2017 were retrospectively noted as having right or left ovarian involvement or a tumour mass with right or left overgrowth. Results and discussion: A prominence of left ovarian involvement was observed in our study results. Especially when patients in the first stage of cancer, FIGO stage 1A, were examined, it was obvious that epithelial ovarian cancer tends to commence in the left ovary rather than the right ovary. Conclusion: There is a need for prospective studies with multidisciplinary studies including immunohistopathology to investigate hypotheses such as hormonal susceptibility, which can be postulated as an explanation for the higher frequency of left vs right ovary involvement in EOC

    Similar works