Objective. )e purpose of this study was to describe baseline data on etiological, clinical, laboratory, and management strategies in
Kenyan children and adolescents with Disorders of Sex Development (DSD). Methods. )is retrospective study included patients
diagnosed with DSD who presented at ages 0–19 years from January 2008 to December 2015 at the Kenyatta National (KNH) and
Gertrude’s Children’s (GCH) Hospitals. After conducting a search in the data registry, a structured data collection sheet was used
for collection of demographic and clinical data. Data analysis involved description of the frequency of occurrence of various
variables, such as etiologic diagnoses and patient characteristics. Results. Data from the records of 71 children and adolescents
were reviewed at KNH (n � 57, 80.3%) and GCH (n � 14, 19.7%). )e mean age at the time of diagnosis was 2.7 years with a median
of 3 months. )irty-nine (54.9%) children had karyotype testing done. )e median age (IQR) of children with reported karyotypes
and those without was 3.3 years (1.3–8.9) and 8.3 years (3.6–12.1), respectively (p � 0.021). Based on karyotype analysis, 19
(48.7%) of karyotyped children had 46,XY DSD and 18 (46.2%) had 46,XX DSD. )ere were two (5.1%) children with sex
chromosome DSD. Among the 71 patients, the most common presumed causes of DSD were ovotesticular DSD (14.1%) and CAH
(11.3%). Majority (95.7%) of the patients presented with symptoms of DSD at birth. )e most common presenting symptom was
ambiguous genitalia, which