Searches for new physics in high-multiplicity events with little or no missing energy are an important component of the LHC program, complementary to analyses that rely on missing energy. We consider the potential reach of searches for events with a lepton and six or more jets, and show they can provide increased sensitivity to many supersymmetric and exotic models that would not be detected through standard missing-energy analyses. Among these are supersymmetric models with gauge mediation, R-parity violation, and light hidden sectors. Moreover, ATLAS and CMS measurements suggest the primary background in this channel is from t-tbar, rather than W+jets or QCD, which reduces the complexity of background modeling necessary for such a search. We also comment on related searches where the lepton is replaced with another visible object, such as a Z boson.Comment: 23 pages, 12 figures, 1 tabl

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