In this study, we report on the effectiveness of using laser ablationinductively coupled plasma mass spectrometry (LA-ICP-MS) to analyze the compositionof trace elements within root dentinal tissue in permanent teeth. The trace elementdistribution in different dentine regions and age related changes in their concentrationwere investigated using the LA-ICP-MS technique, provided semi-quantitative data for12 trace elements among which Mg, Zn, and Sr ranked as the most abundant. Theresults demonstrated that most of the observed elements display conformity throughoutroot dentinal tissue, except for the higher concentrations of Mg in the cervical area andthe higher levels of Zn measured in the pulpal layer. Alterations in the levels of dentinalSr, Cr, Mn, and Se were also observed in relation to the age of dentinal tissue. Thefindings of this investigation indicate that the combination of EPMA and LA-ICP-MSmeasurements may prove instrumental to the further research of this topic in the future
