Huang, Weijuan

Koidis, Anastasios

Lei, Hongtao

Li, Xiangmei

Wei, Xiaoqun

Wei, Xiaoyi

Wu, Shaozong

Xu, Zhenlin

Zhong, Peng

Food fraud is currently a growing global concern with far-reaching consequences. Food authenticity attributes, including biological identity, geographical origin, agricultural production, and processing technology, are susceptible to food fraud. Metabolic markers and their corresponding authentication methods are considered as a promising choice for food authentication. However, few metabolic markers were available to develop robust analytical methods for food authentication in routine control. Untargeted metabolomics by liquid chromatography-mass spectrometry (LC-MS) is increasingly used to discover metabolic markers. This review summarizes the general workflow, recent applications, advantages, advances, limitations, and future needs of untargeted metabolomics by LC-MS for identifying metabolic markers in food authentication. In conclusion, untargeted metabolomics by LC-MS shows great efficiency to discover the metabolic markers for the authenticity assessment of biological identity, geographical origin, agricultural production, processing technology, freshness, cause of animals’ death, and so on, through three main steps, namely, data acquisition, biomarker discovery, and biomarker validation. The application prospects of the selected markers by untargeted metabolomics require to be valued, and the selected markers need to be eventually applicable at targeted analysis assessing the authenticity of unknown food samples

Queen's University Belfast Research Portal

Untargeted metabolomics by liquid chromatography‐mass spectrometry for food authentication: A review

Untargeted metabolomics by liquid chromatography‐mass spectrometry for food authentication: A review

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Queen's University Belfast Research Portal