U kontekstu preventivnih mjera protiv velikih boginja ovaj rad bavi se nekim primjerima cijepljenja u kotaru Kopar u prvoj polovini 19. stoljeća, a osobito općim ponovnim cijepljenjem (1833) i cijepljenjem djece (1835), koje provodio je koparski kotarski liječnik Gian Andrea de Manzoni. Tijekom njegovog djelovanja redovito se provodilo cijepljenje djece i u gradu i u njegovom okruženju, osobito u ruralnim krajevima kotara, međutim u vrijeme izravne opasnosti od bolesti provodilo se i ponovno cijepljenje djece i odraslih. Istraživanjem sačuvanih nominalnih popisa cijepljenih, koji su bili korišteni prvi put, prezentirana je statistička analiza, koja otkriva starosnu i socijalnu strukturu cijepljene populacije, a osim toga dodana su neka polazišta za odraz o dometu tih mjera i njihove efikasnosti. Istraživanje ponekad je problematično u kvantitativnom plasmanu cijepljenih u kontekstu prisutnog stanovništva na tom području, a pitanja koja osim toga ostaju otvorena, odnose na mehanizme kroz koje vlasti su dosegnule ciljnu populaciju, a i na utjecaj odnosa prema ovoj praksi na njezin stvarni domet.In the context of preventive measures against smallpox, this paper deals with some examples of vaccination which was carried out in the Koper district in the first half of the 19th century with special emphasis on general revaccination (1833) and vaccination of children (1835) which were promoted by the district physician Gian Andrea de Manzoni. In the time of his duty, the vaccination was regularly carried out in the town of Koper as well as in its surrounding, mostly rural localities within the district. Besides that, the revaccination of children and adults took place in case of the direct threat of the disease. With the analysis of existing nominative registers of the vaccinated, which are here discussed for the first time, a statistical research dealing with the vaccinated population structure by age and social status is being proposed, together with some starting points for reflection on the range and effect of these preventive measures. However, the author confronts some difficulties in the quantitative contextualization of the vaccinated within the present population of the area. Finally, some remaining questions regard also the mechanisms for persuading the population into the vaccination and the influence of the common attitude towards this practice on its actual range
