Abmayr

Avinoam

Bour

Chen

Dworak

E. H. Chen

Edwards

F. Luo

F. Marikar

Galletta

Gotwals

Islam

J. H. Kim

Johnston

K. Murnen

K. Shilagardi

Massarwa

McCartney

McNally

Mohler

Ogle

Oren-Suissa

P. Jin

Podbilewicz

R. Duan

Rochlin

Ruiz-G  mez

Rust

S. Li

Schafer

Schwander

Sens

Tabata

Yanagawa

To Fuse or Not to Fuse?
          
            Cell-cell fusion is poorly understood, although we know that in the nematode,
            Caenorhabditis elegans
            , it involves cell-surface fusogens and in the fly,
            Drosophila
            , the actin cytoskeleton plays a role.
            
              Shilagardi
              et al.
            
            (p.
            359
            ) reconstituted a high-efficiency, inducible cell-fusion culture system, in which they found that the
            C. elegans
            fusogen, Eff-1, induced a low level of cell-cell fusion that was enhanced by coexpression with a cell adhesion molecule, Sticks and stones (Sns), required for myoblast fusion in
            Drosophila.
            Sns-enhanced cell-cell fusion was mediated by dynamic actin polymerization that generated invasive membrane protrusions at sites of fusion.
          </jats:p

Khurts Shilagardi

Shuo Li

Fengbao Luo

Faiz Marikar

Rui Duan

Peng Jin

Ji Hoon Kim

Katherine Murnen

Elizabeth H. Chen

Crossref

Science

Actin-Propelled Invasive Membrane Protrusions Promote Fusogenic Protein Engagement During Cell-Cell Fusion

Actin-Propelled Invasive Membrane Protrusions Promote Fusogenic Protein Engagement During Cell-Cell Fusion

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