History of wine consumption begins in prehistoric periods; a vast majority
of early nations was giving divine status to one of the most popular alcoholic
drinks, simply made by fermentation of Vitis vinifera grapes. Nowadays, a
unique consensus on the harmfulness of alcohol consumption exists among
whole scientific society, but wine stays an exception. Numerous epidemiological
studies are showing its tremendous benefit on consumer’s cardiovascular
health status, and numerous in vitro studies show antimicrobial, anticancer,
antidiabetic, hormonal and other beneficial biological effects. Researchers are
attributing healing properties of wine to its high content of herbal secondary
metabolites, like tannins and polyphenols with the emphasis on phytoalexin
resveratrol. However, it is still hard to determine the exact physiological mechanisms
of those presumably beneficial compounds and therefore, more effort
in new sophisticated research is required