The role that liquid biofuels will play in future energy systems will depend on biomass-to-energy supply chain to overcome the barriers that may hinder the development and international trade, as well as a sustainable and efficient production of biomass resources. This research paper is based on an extensive literature review, and its purpose is to identify and to investigate the variables that, throughout the agricultural biomass-to-energy supply chain, give rise to the barriers that are common to most varieties of biomass. For achieving it and to assess the effects of referred barriers were used techniques of the Soft Systems methodology. Although biomass-to-energy supply chains are diverse in terms of pattern and operations, the characteristic of the barriers involved in the research provides a broad insight into the issues and challenges to define consistent strategies and interventions for overcoming them. So, this review might be useful for further research related to agricultural biomass-to-energy supply chain optimization that is needed
