Optimization of Bioprocess Variables for Fungal Lipase Production using Statistical Experimental Design: A Mini Review

Abstract

Lipases hold the important role in wide spectrum of biotechnological applications. Lipases are unique, not only due to their ability to perform hydrolysis of fats into fatty acids and glycerol at the water-lipid interface, but also can reverse the reaction in non-aqueous media. Currently, the studies revealed that fungi are the one of choice for lipase production. Some important lipase-producing fungal genera include Aspergillus, Penicillium, Rhizopus, Candida, Geotrichum, etc. The development of response surface methodology applied to optimize fungal lipase production is discussed.

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