American Society for Biochemistry and Molecular Biology (ASBMB)
Abstract
Journal ArticleWe describe the isolation and characterization of two peptide toxins from Conus ermineus venom targeted to nicotinic acetylcholine receptors (nAChRs). The peptide structures have been confirmed by mass spectrometry and chemical synthesis. In contrast to the 12-18 residue, 4 Cys-containing α-conotoxins, the new toxins have 30 residues and 6 Cys residues
