University of Utah, Associated and Regional University Pathologists (ARUP) Institute for Clinical and Experimental Pathology
Abstract
AbstractRecent studies have employed isotope-coded affinity tags (ICAT) in concert with tandem mass spectrometry (MS/MS) to assess differential expression of proteins on a proteomic scale and perform unbiased quantitative comparisons between samples from different physiological or disease states. We sought to determine the performance characteristics and analytical profile of ICAT-based quantitative proteomics studies using proteins released by follicular lymphoma (FL)-derived cells as a model system
