Spencer S. Eccles Health Sciences Library, University of Utah
Abstract
The pathogenesis of thyroid-associated ophthalmopathy (TAO) is still unclear, although several evidences suggest that it is autoimmune. Two candidate auto-antigens are TSH-R and the novel protein, forkhead box P1 (FOXP1). This study is aimed to characterize the expression of FOXP1 in the extrocular muscle (EOM) and explore its function in muscle cells