Optic neuritis in patients with anti-MOG spectrum disorder: MRI and clinical features

Abstract

In adults, the spectrum of MOG antibody-associated demyelinating diseases(MOG-SD) constitutes a recently described and challenging entity. It encompasses almost 25% of patients with neuro-myelitis optica spectrum disorder being negative for antiaquaporine 4 antibodies(AQP4). The most frequently observed manifestation is optic neuritis(ON), more rarely myelitis. From the first publications, demographics and clinical presentation of these patients appeared different from those with AQP4-Abs

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