Azithromycin as a possible neuroprotective drug in mouse model of optic nerve crush

Abstract

Azithromycin (AZ) is a macrolide antibiotic approved worldwide to treat a variety of community-acquired; infections. Recently, it was reported that AZ reduced oxidative stress in lung ischemia and protected mice; following ischemic stroke. Optic nerve crush (ONC) is a common model simulating optic neuropathy and is used in this study to evaluate the neuroprotective effect of AZ

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