Macroscopic EEG fields can be an explicit top-down neocortical mechanism that
directly drives bottom-up processes that describe memory, attention, and other
neuronal processes. The top-down mechanism considered are macrocolumnar EEG
firings in neocortex, as described by a statistical mechanics of neocortical
interactions (SMNI), developed as a magnetic vector potential A. The
bottom-up process considered are Ca2+ waves prominent in synaptic
and extracellular processes that are considered to greatly influence neuronal
firings. Here, the complimentary effects are considered, i.e., the influence of
A on Ca2+ momentum, p. The canonical
momentum of a charged particle in an electromagnetic field, Π=p+qA (SI units), is calculated, where the charge of
Ca2+ is q=−2e, e is the magnitude of the charge of an
electron. Calculations demonstrate that macroscopic EEG A can be
quite influential on the momentum p of Ca2+ ions, in
both classical and quantum mechanics. Molecular scales of Ca2+
wave dynamics are coupled with A fields developed at macroscopic
regional scales measured by coherent neuronal firing activity measured by scalp
EEG. The project has three main aspects: fitting A models to EEG
data as reported here, building tripartite models to develop A
models, and studying long coherence times of Ca2+ waves in the
presence of A due to coherent neuronal firings measured by scalp
EEG. The SMNI model supports a mechanism wherein the p+qA interaction at tripartite synapses, via a dynamic centering
mechanism (DCM) to control background synaptic activity, acts to maintain
short-term memory (STM) during states of selective attention.Comment: Final draft. http://ingber.com/smni14_eeg_ca.pdf may be updated more
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