A new synthetic approach to pyrrolo[3,2-b]indoles via regioselective formation of pyrrole and intramolecular C[-]N coupling

Abstract

A new synthetic approach for the synthesis of pyrrolo[3,2-b]indoles has been developed in two steps. First step involves electrophilic iodocyclization of protected 2-alkynylanilines to regioselective formation of pyrroles followed by copper catalyzed intramolecular C[sbnd]N coupling