Особенности предложенного алгоритма ведения пациенток репродуктивного возраста, больных лейомиомой матки с различным типом биоценоза влагалища, и оценка его эффективности
Цель исследования — оценить эффективность предложенного алгоритма коррекции биоценоза
влагалища больных миомой матки в репродуктивном возрасте.
Обследовано 216 женщин репродуктивного возраста, больных миомой матки. Эффективность традиционной
и предложенной терапии определяли в зависимости от состояния биоценоза влагалища,
клинического течения заболевания, сравнительной характеристики результатов исследований.
Научная новизна предложенного алгоритма заключается в одновременной коррекции локального
и общего биоценоза организма, в профилактическом применении пробиотиков локального и общего
действия, в назначении перед и после хирургического вмешательства этиотропной терапии.The condition of the vaginal biocenosis affects the general condition of the patient’s
body, the course of the underlying disease and the concomitant pathology. Treatment of vaginal infections
is based on the stage: empirical therapy; etiotropic antibacterial therapy; normalization of microflora and optimization of the state of the vaginal ecosystem; support of vital functions of lactobacilli,
normalization of the function of the vaginal epithelium.
The aim of the study was to evaluate the effectiveness of the proposed algorithm for correcting
the vaginal biocenosis of patients with uterine myoma.
216 patients with uterine myoma were examined. The effectiveness
of traditional and proposed therapy in patients with uterine myoma was determined depending
on the state of the vaginal biocenosis and by clinical signs, in comparison with the initial data
and with each other.
After the proposed therapy, the incidence of dysbiosis
decreased in 2.7 times, vaginitis — in 4. 4 times, exocervicitis with cervical erosion — in 1.4 times,
secondary posthemorrhagic anemia, hyperspolymenorrhea — in 1.7 times, respectively (p>0.05) —
the difference is not reliable. The incidence of discomfort decreased by 2.2 times, pelvic pain, gravity
in the lower abdomen, frequent urination — in 1.6 times, respectively, radiculcal syndrome — in
1.9 times, clinically significant (> 3 lg per 105 cells) human papilloma virus — in 2.4 times (p<0.05).
Thus, the proposed therapy was better by the results of treatment in 2.2 times, or by 12.5 % in relation
to traditional treatment.
The scientific novelty of the proposed algorithm consists in the simultaneous correction
of the local and general biocenosis of the organism, in the preventive application of probiotics of local and
general action, in the appointment before and after the surgical intervention of etiotropic therapy
