For quality engineering researchers and practitioners, a wide number of statistical tools and techniques are available for use in the manufacturing industry. The objective or goal in applying these tools has always been to improve or optimize a product or process in terms of efficiency, production cost, or product quality. While tremendous progress has been made in the design of quality optimization models, there remains a significant gap between existing research and the needs of the industrial community. Contemporary manufacturing processes are inherently more complex - they may involve multiple stages of production or require the assessment of multiple quality characteristics. New and emerging fields, such as nanoelectronics and molecular biometrics, demand increased degrees of precision and estimation, that which is not attainable with current tools and measures. And since most researchers will focus on a specific type of characteristic or a given set of conditions, there are many critical industrial processes for which models are not applicable. Thus, the objective of this research is to improve existing techniques by not only expanding their range of applicability, but also their ability to more realistically model a given process. Several quality models are proposed that seek greater precision in the estimation of the process parameters and the removal of assumptions that limit their breadth and scope. An extension is made to examine the effectiveness of these models in both non-standard conditions and in areas that have not been previously investigated. Upon the completion of an in-depth literature review, various quality models are proposed, and numerical examples are used to validate the use of these methodologies
