Patent foramen ovale (PFO) is associated with high prevalence of stroke and systemic
embolisation. A 53-year-old man had mitral valve thrombus and PFO diagnosed by
echocardiography, in addition to carotid artery stenosis and embolic events including transient
ischemia attack, retinal artery occlusion and left kidney infarct. Surgical removal of the mitral
valve thrombus and concomitant coronary artery bypass were performed under cardiopulmonary
bypass. We believe this is the sole reported case of mitral valve thrombus associated with
a PFO. Due to their embolic potential, concomitant PFOs should be closed during heart
operations, and independent ones deserve interventional management in high-risk patients