We reported a case of large right atrial thrombus which migrated from the inferior vena cava
after acute left ventricular dysfunction due to 5-Fluorouracil cardiotoxicity. The patient had
recurrent episodes of chest pain and dyspnea suggestive of pulmonary thromboembolism and
several days later control echocardiography showed that the right atrial thrombus had disappeared.
The patient was discharged with oral anticoagulant therapy with no further clinical sequele during
an 11 month period but died because of progression of metastatic processes. We hypothesized that
initial congestive heart failure had been a provocative factor for thromboembolic events from
previous thrombus formation at the inferior vena cava. (Cardiol J 2008; 15: 284-285
