We report on a case in which a child died from acute encephalopathy associated with Influenza A( H1N1)pdm. The case pertains to an 8-year-old girl, who was diagnosed with influenza A on the previous day andwas prescribed zanamivir hydrate. She experienced abdominal pain and delirium the next morning, so shewas referred to our hospital. Her level of consciousness at the time of consultation was JCS 200. In the brainCT scan, a swollen brain stem and bilateral middle cerebral artery were depicted. She was in a state of respiratoryfailure, and was admitted to the intensive care unit. She was diagnosed with acute encephalopathycaused by Influenza A, and therapeutic brain hypothermia as well as steroid pulse therapy were performed;however, she died on the third day after hospitalization from multiple organ failure
