A 56-year-old woman, suffering from major third degree burns, had right hypochondric pain and fever on her 57th post-burn day. A diagnosis of acute acalculous cholecystitis was established by ultrasonography. Despite effective drainage of the gallbladder through PTGBD, the patient died of ARDS and septic shock on the 73rd post-burn day. Acute acalculous cholecystitis is an uncommon but potentially lethal complication in severely burned patients. Ultrasonography is helpful in early diagnosis and drainage. PTGBD is indicated in severely burned patients
