Synthesis and Evaluation of a Lead Binding Peptoid

Abstract

Previous research had shown that peptides with the amino acid sequence GGGTNTLSNNGGG have an affinity for binding lead particles in solution. The aim of this project is to prepare a peptoid with binding affinity for lead. Initial results show a 27:1 lead to peptoid binding with an average 14% lead decrease in the presence of 1.31× 10-5 moles of the peptoid. The decrease in the lead concentration found in the solution coupled with the reusability of the peptoid resin are promising results for peptoid use in lead contaminated water supplies.https://digitalcommons.humboldt.edu/inrsep_posters/1004/thumbnail.jp

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