OLIVEIRA, Conceição Maria de

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Validação dos anticorpos monoclonais Og4C3 e AD12 no diagnóstico da filariose bancroftiana em inquérito populacional

Cadernos Espinosanos (E-Journal)

Rev. Inst. Med. trop. S. Paulo45(6):332, November-December, 2003*This thesis is available at the Library of the Instituto de Medicina Tropical de São PauloSUMMARY OF THESIS*OLIVEIRA, Conceição Maria de - Validação dos anticorpos monoclonais Og4C3 e AD12 no diagnóstico da filariose bancroftiana em inquéritopopulacional. Recife, 2003. (Dissertação de Mestrado - Departamento de Saúde Coletiva do Centro de Pesquisas Aggeu Magalhães - CPqAMda Fundação Oswaldo Cruz/FIOCRUZ).VALIDATE OF OG4C3 ELISA AND ICT CARD TEST IN BANCROFTIAN FILARIASIS SURVEYThe classical methods for the diagnosis of bancroftian filariasis bythe way of microscopic examination of thick blood smears, collectedusually at night, are not sensitive enough neither perfectly trustful. Otheravailable methods have been considered as more practical, as the Og4C3ELISA and ICT card test. This work try to validate those methods usinga population survey realized in an endemic area in Northeast of Brazil.Og4C3, ICT and thick blood film, the last used as a gold standard, werecompared with the data of epidemiological surveillance. The Og4C3showed a 96.1% sensibility, a negative predictive value of 98.7% and aprecision of 87.7%. The ICT showed a 94.4% sensibility, a negativepredictive value of 97.1% and a precision of 91.9%. The most usefulmethod is the one which present a higher sensibility and a higher negativepredictive value. This dissertation argues that neither Og4C3 nor ICTcan be considered ideal tests. Notwithstanding, ICT is indicated in thiswork as an adequate method to be used in Metropolitan Region of Recife,because of its better general results and because it is the more practical.Conceição Maria de OliveiraAv. Moraes Rego s/n, Campus da UFPE50670-420 Recife-PE, BrasilPhone: (81) 3301-2573E-mail: coliveira@cpqam.fiocruz.br

Validate of OG4C3 ELISA and ICT card test in bancroftian filariasis survey

https://www.revistas.usp.br/rimtsp/article/download/30771/32655

Validação dos anticorpos monoclonais Og4C3 e AD12 no diagnóstico da filariose bancroftiana em inquérito populacional

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