FREITAS, Isabella Nicácio de

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Cadernos Espinosanos (E-Journal)

		 !"# !*This thesis is available at the Library of the Instituto de Medicina Tropical de São PauloSUMMARY OF THESIS*FREITAS, Isabella Nicácio de – Doença celíaca no adulto: casuística de um centro de referência. São Paulo, 2000. ( Dissertação de Mestrado –Faculdade de Medicina da Universidade de São Paulo).CELIAC DISEASE IN ADULTS: CASUISTIC FROM A REFERENTIAL CENTERForty-eight adult patients with celiac disease, between 15 and 68 yearsold (mean: 41 years) were studied. Sixty-seven per cent of the patientswere female and 33% male. Most of the patients were white (98%).The main clinical features were diarrhea (90%), weight loss (70%)and abdominal pain (56%). On the physical exam, the main findingswere pallor (40%), aphthous stomatitis (31%) and arthralgia (23%).Associated disorders also occurred: diabetes mellitus type I,osteoporosis and atopy (6% each), dermatitis herpetiformis anddepression (4% each), hypothyroidism, hyperthyroidism, duodenalcarcinoma and Gilbert syndrome (2% each). The histologic resultsaccording to Marsh criteria (modified by Rostami) were as follows: 10%type I; 21% type II; 19% type IIIa; 17% type IIIb and 33% type IIIc.The sensitivity and specificity for the IgA antiendomysium antibodywere 92 and 100%, respectively, when considering the whole group ofpatients; however, the sensitivity (but not the specificity) decreased to86% when taking into account only the group of patients with mildhistologic alterations (Marsh I, II and IIIa).In general, our results were similar to those described in developedcountries, pointing out that celiac disease might have the same spectrumof presentation regardless of the region studied.

Celiac disease in adults: casuistic from a referential center

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Doença celíaca no adulto: casuística de um centro de referência

https://www.revistas.usp.br/rimtsp/article/download/30471/32355

Doença celíaca no adulto: casuística de um centro de referência

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Cadernos Espinosanos (E-Journal)

Scientific Electronic Library Online - Brazil