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Abstract

Candidiasis is a fungal disease caused by the infection of a fungus. Candida albicans is a normal flora of the oral cavity, pharynx and gastrointerstinal tract, and it. lives in symbiosis with the mixed bacterial flora of the oral cavity. But it is an opportunist and can become a pathogen if the proper environment prevails. Candidiasis occurs in infants and becomes recognizable as thrush. In adults it occurs usually in individuals who have been debilitated secondally to prologed chronic disease and terminal-illness in whom immunosupressive drugs such as adrenal cortical hormone, radiotherapy and long-term antibiotic therapy are administered. Recently, we observed two cases of oral candidiasis of adults. Case 1 was 54 years old male. He was subjected to a gastric resection and was prescribed a cartinostatic agent three months hence. Recently, he experienced a fever (suspected as pneumonia) and was given some unknown antibiotics and adrenal cortical hormone. Big white plaques were seen in the lower lip and he felt pain by contact. Case 2 was a 76 years old female. The patient underwent a resection of a malignant tumor of the cheek, a radical neck dissection and a skin grafting for the cheek 6 months hence in our clinic. A remarkable quantity of carcinostatic agents and antibiotics was administered 6 months hence. Recently, she had a feber (suspected as pneumonia) and was prescribed penicillin and adrenal cortical hormone. So many small white plaques in left ceek were noted and she complained of pain when touched. Both cases were treated effectively by mycostatin gargle