<原著>顎口腔領域悪性腫瘍の臨床統計的研究

Abstract

Clinico-statistical observations were made of 48 cases of malignant tumors of the oral and maxillofacial regions from 1978 to 1995 at the Department of Oral Surgery, School of Dentistry, Health Sciences University of Hokkaido. The results were as follows: 1) Of 48 patients, 35 were male and 13 were female (2. 7:1). The mean age was 60. 7. 2) Of the cases, 30 (62.5%) were referred by private dental clinics. 3) Histopathologically, 37 cases (77.1%) were diagnosed to suffer from squamous cell carcinomas, 4 cases (8.3%) with malignant tumors in the salivary glands, 3 cases (6.3%) with malignant lymphomas, 2 cases (4.2%) with malignant melanomas, and 2 cases (4.2%) with metastatic tumors from other regions. 4) In 43 cases of primary malignant tumors, the most commonly affected site was the tongue (32.6%) followed by the lower gingiva (23.3%), upper gingiva (11.6%), floor of the mouth (11.6%), and mucosa of the cheeks (7.0%) and others (13.9%). 5) By the UICC (1987) stage grouping, 63.1% of 38 cases of primary carcinomas were clinically in the advanced stages III and IV. 6) In 36 primary oral cacinomas, 21 cases were treated by chemotherapy (C) + surgery (S), 8 cases by surgery alone, 1 case by irradiation (R) + surgery, 1 case by (C+S+R), and 5 cases by chemotherapy alone. 7) The 5-year cumulative survival rate was 55.2% in the 36 primary carcinoma cases