thesis
Biomarkers of fever: from bench to bedside
- Publication date
- 28 March 2014
- Publisher
- __Abstract__
This thesis aims to study biomarkers in inflammation and infection, with a special focus
on the distinction between infectious and non-infectious fever. The thesis consists of
three parts, part I being this introduction, in which the concept of fever in infectious and
non-infectious disease is discussed. Furthermore, in this part we provide an overview of the
epidemiology of febrile disease, as studied both in a general hospital in the Netherlands and
in a general hospital in Curaçao. Also, a review of current literature on biological markers in
non-infectious fever is given. Part II describes our clinical studies with focus on biomarkers
in different cohorts of patients with infectious and non-infectious fever. In part III, we summarize
the findings of this thesis and discuss future research.
