Allington, Douglas

Colucci, Vincent J.

Docktor, William J.

Hale, Katherine S.

Hudgins, Gayle A.

English

University of Montana

University of Montana ScholarWorks at University of Montana Syllabi Course Syllabi 1-2014 PHAR 554.01: Therapeutics IV William J. Docktor University of Montana - Missoula, william.docktor@umontana.edu Douglas Allington University of Montana - Missoula, douglas.allington@umontana.edu Gayle A. Hudgins University of Montana - Missoula, gayle.hudgins@umontana.edu Vincent J. Colucci University of Montana - Missoula, vincent.colucci@umontana.edu Katherine S. Hale University of Montana - Missoula, katherine.hale@umontana.edu Follow this and additional works at: https://scholarworks.umt.edu/syllabi Let us know how access to this document benefits you. Recommended Citation Docktor, William J.; Allington, Douglas; Hudgins, Gayle A.; Colucci, Vincent J.; and Hale, Katherine S., "PHAR 554.01: Therapeutics IV" (2014). Syllabi. 2304. https://scholarworks.umt.edu/syllabi/2304 This Syllabus is brought to you for free and open access by the Course Syllabi at ScholarWorks at University of Montana. It has been accepted for inclusion in Syllabi by an authorized administrator of ScholarWorks at University of Montana. For more information, please contact scholarworks@mso.umt.edu.  1  Therapeutics IV - Pharmacy 554  -  Spring 2014  Course Coordinator: WJD   M, T  1310-1500     SB 114 Instructors:     F 1510-1730 (Tests) wjd Bill Docktor  william.docktor@umontana.edu  5713 dra Doug Allington douglas.allington@umontana.edu    2498 kh Katherine Hale katherine.hale@umontana.edu  4647 gac Gayle Hudgins gayle.hudgins@umontana.edu   6495  vjc Vince Colucci  vincent.colucci@umontana.edu   4634  sn Sarah Norman  sarah.norman@providence.org  520 784-8205   Disabilities Students with disabilities may request reasonable modifications by contacting me.  The University of Montana assures equal access to instruction through collaboration between students with disabilities, instructors, and Disability Services for Students (DSS).  “Reasonable” means the University permits no fundamental alterations of academic standards or retroactive modifications.  For more information, please consult http://www.umt.edu/disability.  If you think you may have a disability adversely affecting your academic performance, and you have not already registered with DSS, please contact DSS in Lommasson 154.   I will work with you and DSS to provide an appropriate accommodation.  The University requires the following statement on all syllabi: “All students must practice academic honesty.  Academic misconduct is subject to an academic penalty by the course instructor and/or a disciplinary sanction by the University.  All students need to be familiar with the Student Conduct Code.  The Code is available for review online at http://life.umt.edu/vpsa/student_conduct.php   Material and Resources Required Texts: DiPiro: Pharmacotherapy APhA: Handbook of Nonprescription Drugs Goodman & Gilman's Pharmacological Basis of Therapeutics  Boh’s Pharmacy Practice Manual: A Guide to the Clinical Experience Susan Stein,   OR a diagnostic and laboratory book A medical dictionary Optional Texts: Clinical Pharmacokinetics Pocket Reference, John Murphy  (strongly recommended)    Young, Koda-Kimble:  Applied Therapeutics Course Orientation Pharmacotherapy is drug therapy.  It involves the application of drug knowledge to the treatment of patients.  This requires organizational skills, critical thinking skills, problem solving skills, communication skills, and creativity as well as an understanding of drugs, diseases, and people.  This course will focus on the analytical, synthesizing, and evaluative skills needed to assess drug therapy and formulate and communicate a solution.  Although knowledge is not the primary focus, you will learn much information by using it to solve pharmacotherapeutic   2 problems.       Pharm. D. Program Outcomes addressed by this course:  IA, IB, III, VIA, VIB, VIIA, VIIIA,VIIIC   These outcomes may be found on the program website (under “current students” then “documents”) but are reproduced for you below:  http://pharmacy.health.umt.edu/documents-and-links  University of Montana - Doctor of Pharmacy Program Mission and Outcomes Statement (9-10-09)  The mission of the Doctor of Pharmacy Program is to prepare future pharmacists, in both formal and informal learning environments, to provide patient-centered and population-based care and to manage the systems within which pharmacists work while fostering professionalism, leadership and advocacy, interprofessional collaboration, self-directed learning, cultural competency and scholarship.  In achieving the mission of the Doctor of Pharmacy Program, graduates will have the ability* (knowledge, skills, attitudes and values) to:  I. Provide patient-centered care A. Integrate and apply biomedical, pharmaceutical, social/behavioral/administrative, and clinical sciences B. Ensure optimal pharmacotherapy for patients  II. Communicate effectively with patients, families, caregivers, and health care professionals  III. Use critical thinking and problem solving skills to enhance patient care  IV. Work effectively within an interprofessional team  V. Manage and utilize resources of the health care system for the benefit of individual and public health. A. Promote patient and public safety B. Perform quality assurance techniques to improve the medication use system C.  Seek to reduce health care disparities.  VI. Efficiently utilize information resources and technology A. Identify, retrieve and interpret relevant professional literature B. Communicate evidence-based information to other health care providers, patients, and the public  VII. Promote public health A. Promote health improvement, wellness, and disease prevention B. Solve, or contribute to, solutions to public health problems  VIII. Practice professionally A. Apply ethical, social, legal and economic principles to practice B. Respond to patients’ needs in a culturally sensitive manner C. Apply practice standards to optimize patient care D. Maintain professional competence by becoming a self-directed learner   IX. Be a good citizen, demonstrate leadership and contribute to the community  X. Engage in scholarly activity A. Use a scholarly approach to become an agent of change to advance pharmacy practice  3 B. Demonstrate a commitment to life-long learning  *Each ability is many faceted.  The ACPE Accreditation Standards, Guidelines, and Appendices   (http://www.acpe-ccredit.org/pdf/ACPE_Revised_PharmD_Standards_Adopted_Jan152006.DOC) and   the CAPE Educational Outcomes 2004 and Supplements   (http://www.aacp.org/Docs/MainNavigation/Resources/6075_CAPE2004.pdf)   describe these abilities in much more detail and can be consulted for further definition.  Goals of the Course  To develop and utilize organizational skills, critical thinking skills, problem solving skills, and communications skills to benefit patients.  To promote the students‟ understanding of pathophysiology of cardiovascular, psychiatric, and neurological disorders with particular emphasis on the facets of diseases that are amenable to drug therapy.  To augment the student's understanding of the management of cardiovascular, psychiatric, and neurological disorders with particular emphasis on pharmacotherapy.  To familiarize the student with the proper use of drugs in a clinical setting.  To develop the student‟s awareness of factors that should be considered prior to selection of a drug and the appropriate parameters that should be monitored for therapeutic as well as undesired effects.  Performance Objectives  Upon completion of this course, each student shall be able to:  Organize patient information into a problem list with supporting data.  Relate the pathophysiology of a disease to the known or purported action(s) of a drug.  Evaluate the seriousness of a disorder based on the signs and symptoms related to a diagnosed problem, and: --determine the necessity of drug therapy, --when applicable, choose the proper drug, dosage, and/or drug product for the situation.   Determine the role of non-pharmacologic therapy.  Tailor the drug therapy to an individual based on patient characteristics and pharmacokinetic and pharmacoeconomic principles.  Monitor the appropriate parameters of a disease to determine if the patient is responding  4 positively to therapy.  Monitor for adverse drug reactions and exacerbation of underlying patient problems resulting from drug therapy.  Identify potential drug-drug interactions, and put forth an appropriate plan to mitigate these issues.  Identify and formulate solutions for specific drug related problems  Evaluate potential solutions for a given patient‟s drug related problem to optimize his/her pharmacotherapy.   Communicate pharmacotherapeutic suggestions effectively.  More Specific Goals and Objectives are attached to the handout for each topic.  Student Responsibilities and Obligations  To do assigned readings and studying from the texts before the corresponding class sessions.  To attend and participate in class discussions.  To perform clinical assessments and recommendations successfully on take-home cases and write professional consultations.   To perform satisfactorily on tests.  Testing and Grading: Your grade is determined by your responses on take-home cases and tests.  Both take-homes and tests require you to utilize material that you were exposed to and should have learned in prior classes.  Take-home cases should be evaluated to identify any drug related problem and propose solutions to these problems.  The rationale for your recommendation is an essential component and should be stated completely.  The “why” is more important than the “what”.  More specific information for what is needed in the answer is provided in the rubric for each case.  Unless other arrangements have been made with the course coordinator (wjd) prior to the due date, these assignments must be turned in on time if credit is to be awarded.  Discussion of these take-home assignments among students is encouraged.  However, each student must write their own answers. No other student should ever see your written response; this will be considered academic dishonesty.  Identical, or virtually identical, responses will be considered academic dishonesty and lead to failure of the course.  .              5 Pharmacokinetics topics will be graded in two ways:  test questions and take-home cases.  The homework should include: -an evaluation of the patient and current dosage of the drug, -calculations (if needed) including (at a minimum) formulae, numbers substituted in, and the answer, and -a written consultation to the physician with your evaluation, recommendations, and justification.  The test questions are usually:  1)  evaluate this persons therapy and state if you agree or disagree.  If you agree, state why.  If you disagree, state why, suggest an alternative, and justify your choice, or 2)  Critique this prescription.  If you agree, state why.  If you disagree, state why, suggest an alternative, and justify your choice.     There will be four tests, two cardiac, one psychiatric, and one neurologic.  These will be open book and open notebook.  No electronic devices are allowed.  Questions will be case scenarios, similar to take-home cases.  You will need to organize data, evaluate, recognize problems, and generate, justify and communicate solutions.  Academic dishonesty, also known as cheating, will not be tolerated in any form.  Academic dishonesty will result in failure of the course. One form of academic dishonesty is plagiarism. According to the Online Writing Lab of Purdue University, last updated on March 27, 2013 by Karl Stolley, Allen Brizee, Joshua M. Paiz, plagiarism “is the uncredited use (both intentional and unintentional) of somebody else's words or ideas.”  As for the definition of plagiarism as defined on the website www.plagiarism.org (2013) “All of the following are considered plagiarism: turning in someone else's work as your own copying words or ideas from someone else without giving credit failing to put a quotation in quotation marks giving incorrect information about the source of a quotation changing words but copying the sentence structure of a source without giving credit copying so many words or ideas from a source that it makes up the majority of your work, whether you give credit or not (see our section on "fair use" rules)”  Grading: Your grade in Therapeutics IV is based on total points.  A point is a point, whether it is on a test or on a homework assignment.  Grades are based on the original curve (see below);  NOT  the 90/80/70/60 to which you have become accustomed..   At the end of the course, I will put the total points in a distribution and  look for natural breaks to divide between grades.  A, B, C, D, or F are the only possibilities, there are no +/-„s.    There are a few guarantees.  1. All assignments must be completed or you will fail the course no matter how many points you have accumulated. 2. You are guaranteed, at least  a(n):   A if you achieve > 93% of the highest grade   B if you achieve > 86% of the highest grade   C if you achieve  > 79% of the highest grade  6   D if you achieve > 72% of  the highest grade. I calculate this percentage on the basis of the highest grade achieved in the class.  I figure the rest are our fault.  Therefore, the percentage on any given assignment is irrelevant.  These cuts are not absolute.  They will never go up.  They often go down, based on gaps between groups of students.      An assessment schedule is attached.  Grades are presented and kept on Moodle.  This is not intended to be an online course.  If faculty want to post materials they can, but not all course materials will be available online.     Syllabus: Reading and studying are REQUIRED.  The contents of the assigned pages, some of which may not be discussed in class, will be included on cases and tests.  You are expected to have read and STUDIED each chapter and be ready to discuss it before the assigned class time.  In addition, you are expected to bring what you have learned in previous classes, such as pharmacokinetics, pharmacology, pharmaceutics, and therapeutics.   Chapter is chapter of DiPiro, eighth edition) as a Study Assignment to be done before class  Day Month Date Topic Instructor Chapter M Jan 27 Introduction Ischemic Heart Disease wjd vjc  23 T Jan 28 Ischemic Heart Disease vjc 24 M Feb 03 Electrocardiograms Dysrhythmias vjc 17 18 T  04 Dysrhythmias vjc 25 M  10 Dysrhythmias vjc  T  11 Digoxin Pharmacokinetic – bring calculators wjd 8 M  17 Presidents‟ Holiday   T  18 Hypertension  kh 19, JNC-8 F  21 Test One  thru Dig PK  1510-1740 SB114/117   7 M  24 Hypertension Lipid kh 28 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce ASCVD Risk in Adults T Feb 25 Lipid kh  M Mar 03 Alcohol withdrawal Heart Failure wjd vjc  20, 21 T  04 Heart Failure vjc 22 M  10 Hemodynamics vjc  T  11 Shock vjc 30, 31 M  17 Schizophrenia sn 76 T  18 Schizophrenia Depression sn   77 F  21 Test two HTN thru Shock  1510-1740 SB114/117  M  24 Depression Bipolar Disorder sn  78 T  25 Bipolar Disorder Anxiety Disorders sn wjd  79 M Mar 31 Spring    T Apr 01 Break   M  07 Anxiety Disorders wjd 80 T  08 Sleep Disorders wjd 81 M  14 ADHD wjd 72 T  15 ADHD Anticonvulsant Pharmacokinetics  dra   F  18 Test three   schiz thru sleep 1510-1740 SB114/117  M  21 Anticonvulsant Pharmacokinetics Seizures dra 65 T  22 Seizures dra 66 M  28 Parkinson‟s disease  68 T Apr 29 Dementia gah 63  8 M May 05 Multiple Sclerosis Spinal Cord Injury dra 64 T  06 in lieu of tests   M  12 Test 4 ADHD thru SCI   1310-1540 S SB169   Assessment Schedule   (*due during break week or a holiday, so plan for it)  Instructor Points Assessment Due Student Due to Instructor vjc 15 Ischemic Heart Disease 1/28 2/4 vjc 30 Dysrhythmias 2/10 2/17 wjd 10 Digoxin Pharmacokinetics 2/11 2/18  55    kh 15 Hypertension  2/24 3/3 kh 15 Lipids 2/25 3/4  55 Test One  1510-1730 thru Dig PK    SB114/117 2/21 2/21 wjd 5 Alcohol withdrawal 3/3 3/10 vjc 15 Heart Failure 3/4 3/11 vjc 10 Hemodynamics 3/10 3/17 en 10 Shock 3/11 3/18  70 Test two HTN thru Shock  1510-1740 3/21 3/21 wjd 15 Schizophrenia 3/18 3/25 wjd 10 Depression 3/24 3/31* wjd 10 Bipolar Disorder 3/25 4/1* wjd 15 Anxiety 4/7 4/14 wjd 10 Sleep Disorders 4/8 4/15  60 Test three  Schiz thru sleep 1310-1530 SB 114/117 4/18 4/18 wjd 15 ADHD 4/15 4/22 dra 10 Anticonvulsant Pharmacokinetics 4/21 4/28 dra 15 Seizure Disorders 4/22 4/29 dra 10 Parkinson‟s 4/28 5/5 gah 10 Dementia 4/29 5/6 dra 5 Multiple Sclerosis 5/6 5/13 dra 5 Spinal Cord Injury 5/6 5/13  70 Test Four ADHD thru SCI  1310-1540       SB169 5/14 5/14  

PHAR 554.01: Therapeutics IV

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PHAR 554.01: Therapeutics IV

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