Farley, Amanda

Greenfield, Sheila

Ismail, Tariq

Jolly, Kate

krouwel, Matthew

English

Introduction – Hypnotherapy for the treatment of Irritable Bowel Syndrome (IBS) has accumulated a broad evidence base, resulting in its inclusion in the UK National Institute of Health and Care Excellence (NICE) Guidelines in 2008. Although several high quality systematic reviews and meta-analyses of hypnotherapy’s efficacy have been conducted, subgroup analysis of factors which contribute to this are absent. The goal of this systematic review is to evaluate the current literature to identify factors which contribute to its effectiveness.Methods and analysis – We will conduct searches in CINAHL, Cochrane library, Conference Citation Index (science &amp; social science), Embase (excerpta medica), Medline, PubMed, PsycARTICLES, PsychINFO, Science Citation Index-expanded and Social Science Citation Index. Data will be included from randomised (RCTs) and non-randomised controlled trials with a concurrent comparator of hypnotherapy interventions for IBS, reported in English. Two authors will independently review studies for inclusion, with arbitration by a third reviewer if needed. We will assess for risk of bias using the Cochrane Collaboration’s risk of bias tool for RCTs and the Robins-I tool for non-RCTs. Where appropriate a meta-regression analysis of pre-defined subgroups will be conducted using a random effects model. Where quantitative analysis is not possible a narrative description will be given.Discussion – These will be disseminated via peer review journals and at appropriate conferences. The results may be of use in establishing the most efficient formulation of services delivering hypnotherapy for IBS

University of Birmingham Research Portal

Factors which affect the efficacy of hypnotherapy for IBS: Protocol for a systematic review and meta-regression

http://pure-oai.bham.ac.uk/ws/files/50053953/manuscript.pdf

Factors which affect the efficacy of hypnotherapy for IBS: Protocol for a systematic review and meta-regression

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University of Birmingham Research Portal