Alexiadis, A

Ariane, M

Barigou, M

Brill, A

Nash, F G B

Vigolo, D

Wen, W

English

M. Ariane

W. Wen

D. Vigolo

A. Brill

F.G.B. Nash

M. Barigou

A. Alexiadis

Crossref

Computers in Biology and Medicine

Modelling and simulation of flow and agglomeration in deep veins valves using discrete multi physics

The hemodynamics in flexible deep veins valves is modelled by means of discrete multi-physics and an agglomeration algorithm is implemented to account for blood accrual in the flow. Computer simulations of a number of valves typologies are carried out. The results show that the rigidity and the length of the valve leaflets play a crucial role on both mechanical stress and stagnation in the flow. Rigid and short membranes may be inefficient in preventing blood reflux, but reduce the volume of stagnant blood potentially lowering the chances of thrombosis. Additionally, we also show that in venous valves, cell agglomeration is driven by stagnation rather than mechanical stress.</p

University of Birmingham Research Portal

http://pure-oai.bham.ac.uk/ws/files/42570314/Ariane_et_al_Modelling_and_simulation_Computers_in_Biology_and_Medicine_201.pdf

Modelling and simulation of flow and agglomeration in deep veins valves using discrete multi physics

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University of Birmingham Research Portal

University of Birmingham Research Portal