A Gasber

A Korte

Adam H. Price

AE Anastasio

AL Garcia-Oliveira

AL Price

Alex Douglas

AN Famoso

Andrew A. Meharg

BM Waters

Brett Lahner

C Toomajian

CW Tung

D Mondal

David E. Salt

EE Adomako

Elena Yakubova

Fang-Jie Zhao

G Sun

Gareth J. Norton

GC Eizenga

Georgia C. Eizenga

GJ Norton

Guilan Duan

H Tomatsu

I Baxter

J Yu

J Zhang

Jauhar Ali

JCR Stangoulis

JF Ma

K Cui

K Lu

K Ohno

K Zhao

KA Mather

KL Fitzpatrick

Lee Tarpley

M Tejada-Jimenez

M Yuan

M. Rafiqul Islam

Mary Lou Guerinot

ML Kile

MW Horton

PJ White

PN Williams

R Graham

R Tuli

RR Mendel

S Atwell

S Lee

SA Ramesh

Shannon R. M. Pinson

Shofiqul Islam

SL Jiang

SP Kiani

Steve P. McGrath

T Agusa

TR Pillai

W Maret

X Huang

X Yang

X Zhang

XY Xu

Y Ishimaru

Y Li

Y Lu

Y Zeng

Yongguan Zhu

YZ Xing

ZU Ahmed

PLoS ONE

English

PubMed

Norton Gareth J.

Douglas Alex

Lahner Brett

Yakubova Elena

Guerinot Mary Lou

Pinson Shannon R. M.

Tarpley Lee

Eizenga Georgia C.

McGrath Steve P.

Zhao Fang-Jie

Islam M. Rafiqul

Islam Shofiqul

Duan Guilan

Zhu Yongguan

Salt David E.

Meharg Andrew A.

Price Adam H.

Public Library of Science (PLOS)

 L.) Grown at Four International Field Sites

Norton, G. J.

Douglas, A.

Lahner, B.

Yakubova, E.

Guerinot, M. L.

Pinson, S. R. M.

Tarpley, L.

Eizenga, G. C.

McGrath, S. P.

Zhao, F-J.

Islam, M. R.

Islam, S.

Duan, G.

Zhu, Y.

Salt, D. E.

Meharg, A. A.

Price, A. H.

Rothamsted Repository

Genome wide association mapping of grain arsenic, copper, molybdenum and zinc in rice (Oryza sativa L.) grown at four international field sites

Norton, Gareth J.

Douglas, Alex

Lahner, Brett

Yakubova, Elena

Guerinot, Mary Lou

Pinson, Shannon R. M.

Tarpley, Lee

Eizenga, Georgia C.

McGrath, Steve P.

Zhao, Fang-Jie

Islam, M. Rafiqul

Islam, Shofiqul

Duan, Guilan

Zhu, Yongguan

Salt, David E.

Meharg, Andrew A.

Price, Adam H.

Ali, Jauhar

Texas A&M University

Genome Wide Association Mapping of Grain Arsenic, Copper, Molybdenum and Zinc in Rice (Oryza sativa L.) Grown at Four International Field Sites

The mineral concentrations in cereals are important for human health, especially for individuals who consume a cereal subsistence diet. A number of elements, such as zinc, are required within the diet, while some elements are toxic to humans, for example arsenic. In this study we carry out genome-wide association (GWA) mapping of grain concentrations of arsenic, copper, molybdenum and zinc in brown rice using an established rice diversity panel of ~300 accessions and 36.9 k single nucleotide polymorphisms (SNPs). The study was performed across five environments: one field site in Bangladesh, one in China and two in the US, with one of the US sites repeated over two years. GWA mapping on the whole dataset and on separate subpopulations of rice revealed a large number of loci significantly associated with variation in grain arsenic, copper, molybdenum and zinc. Seventeen of these loci were detected in data obtained from grain cultivated in more than one field location, and six co-localise with previously identified quantitative trait loci. Additionally, a number of candidate genes for the uptake or transport of these elements were located near significantly associated SNPs (within 200 kb, the estimated global linkage disequilibrium previously employed in this rice panel). This analysis highlights a number of genomic regions and candidate genes for further analysis as well as the challenges faced when mapping environmentally-variable traits in a highly genetically structured diversity panel

Norton, Gareth J

Lahner, Brett C

Pinson, Shannon RM

Eizenga, Georgia C

McGrath, Steve P

Islam, M Rafiqul

Salt, David E

Meharg, Andrew A

Price, Adam H

Purdue E-Pubs

Genome Wide Association Mapping of Grain Arsenic, Copper, Molybdenum and Zinc in Rice (Oryza sativa L.) Grown at Four International Field Sites.

The mineral concentrations in cereals are important for human health, especially for individuals who consume a cereal subsistence diet. A number of elements, such as zinc, are required within the diet, while some elements are toxic to humans, for example arsenic. In this study we carry out genome-wide association (GWA) mapping of grain concentrations of arsenic, copper, molybdenum and zinc in brown rice using an established rice diversity panel of,300 accessions and 36.9 k single nucleotide polymorphisms (SNPs). The study was performed across five environments: one field site in Bangladesh, one in China and two in the US, with one of the US sites repeated over two years. GWA mapping on the whole dataset and on separate subpopulations of rice revealed a large number of loci significantly associated with variation in grain arsenic, copper, molybdenum and zinc. Seventeen of these loci were detected in data obtained from grain cultivated in more than one field location, and six co-localise with previously identified quantitative trait loci. Additionally, a number of candidate genes for the uptake or transport of these elements were located near significantly associated SNPs (within 200 kb, the estimated global linkage disequilibrium previously employed in this rice panel). This analysis highlights a number of genomic regions and candidate genes for further analysis as well as the challenges faced when mapping environmentally-variable traits in a highly genetically structured diversity panel.</p

Queen's University Belfast Research Portal

Genome Wide Association Mapping of Grain Arsenic, Copper, Molybdenum and Zinc in Rice (<i>Oryza sativa L.</i>) Grown at Four International Field Sites

OAKTrust Digital Repository (Texas A&M Univ)

Zhao, Fang Jie

Aberdeen University Research

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Genome wide association mapping of grain arsenic, copper, molybdenum and zinc in rice (Oryza sativa L.) grown at four international field sites

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