Objective: To determine the clinical presentations of brain abscess.Study design: Descriptive study.Place and Duration of Study: Hayatabad Medical Complex Hospital Peshawar Khyber Pakhtoonkhawa from 1st February 2001 to 31st July 2011.Material and Methods: A total 31 patients with symptomatic brain abscess confirmed on CT scan were included in this study. Both gender (male and female) and patients in the age range of 01 – 70 years were included in this study. The patients’ demographic details and clinical manifestation were entered into a semi structured proforma. Data was analyzed through statistical program SPSS version 11.Results: Out of 31 patients, there were 17 (54.8%) males and 14 (45.2%) females. The age of patients ranged from 01 to 70 years. In this study the overall mean age was 32.38 years. Majority of patients 13 (41.9%) were in the age range of 31 – 40 years. Most common clinical presentation of patient were headache in 29 (93.5%) vomiting 22 (71%) and fever 13 (42%) patients.Conclusions: Brain abscess commonly occurred in the third decade of life. Headache vomiting and fever were the most common clinical presentation of brain abscess