Bisphenol A exposure is associated with in vivo estrogenic gene expression in adults

Abstract

addresses: Epidemiology and Public Health, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom.notes: PMCID: PMC3261992types: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov'tEnvironmental Health Perspectives, 2011, Vol. 119, Issue 12, pp. 1788 – 1793 doi: 10.1289/ehp.1103809. Reproduced with permission from Environmental Health Perspectives, http://ehp.niehs.nih.gov/ Copyright ©2011 National Institute of Environmental Health SciencesBisphenol A (BPA) is a synthetic estrogen commonly used in polycarbonate plastic and resin-lined food and beverage containers. Exposure of animal and cell models to doses of BPA below the recommended tolerable daily intake (TDI) of 50 μg/kg/day have been shown to alter specific estrogen-responsive gene expression, but this has not previously been shown in humans