Abu-Sharkh, Basel

Ali, S. A.

Hamad, Esam

King Fahd University of Petroleum and Minerals

Influence of polymer structure on recovery of proteins in two-phase aqueous systems.       
 
Ali, Sk. Asrof; Hamad, E. Z.; Abu-Sharkh, B. F.     
 
Departments of Chemistry & Chemical Engineering,  KFUPM,  Dhahran 31261,  Saudi Arabia.     
 
Book of Abstracts, 218th ACS National Meeting, New Orleans, Aug. 22-26  (1999), MACR-024.   
 
 
Abstract 
 
The partitioning of different proteins in two phase aq. solns. of hydrophobically modified 
polyacrylamide and polyethylene glycol was investigated.  Multiblock copolymers of acrylamide 
with different allyl polymers of varying hydrophobicity and spacer length were synthesized.  The 
allyl polymers are used because they can form hydrophobic domains that are positioned far away 
from steric hindrance caused by acrylamide main chain.  The phase diagrams of the aq. block 
copolymer solns. with polyethylene glycol were studied.  The effect of block hydrophobicity on 
partitioning of the different proteins which are characterized by different mol. wts. and isoelec. 
points was investigated.  Polymers with stronger hydrophobic domains were found to produce 
higher partitioning coeffs. of the proteins. 
 


Influence of polymer structure on recovery of proteins in two-phase aqueous systems

https://eprints.kfupm.edu.sa/id/eprint/9250/1/Influence_of_polymer_structure_on_recovery_of_proteins_in_two_phase_aqueous_systems.pdf

Influence of polymer structure on recovery of proteins in two-phase aqueous systems

Abstract

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