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To be or not to be a piRNA: genomic origin and processing of piRNAs

Authors
Publication date
1 January 2014
Publisher
'Springer Science and Business Media LLC'
Doi
    View on PubMed

    Abstract

    Piwi-interacting RNAs (piRNAs) originate from genomic regions dubbed piRNA clusters. How cluster transcripts are selected for processing into piRNAs is not understood. We discuss evidence for the involvement of chromatin structure and maternally inherited piRNAs in determining their fate

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