CORE
🇺🇦
make metadata, not war
Services
Services overview
Explore all CORE services
Access to raw data
API
Dataset
FastSync
Content discovery
Recommender
Discovery
OAI identifiers
OAI Resolver
Managing content
Dashboard
Bespoke contracts
Consultancy services
Support us
Support us
Membership
Sponsorship
Community governance
Advisory Board
Board of supporters
Research network
About
About us
Our mission
Team
Blog
FAQs
Contact us
Mercury analysis in hair: Comparability and quality assessment within the transnational COPHES/DEMOCOPHES project
Authors
Dominique Aerts
Jürgen Angerer
+39 more
Kerstin Becker
Pierre Biot
Louis Bloemen
Daniela Borošová
Argelia Castaño
Ludwine Casteleyn
Fred Davidson
Irina Dumitrascu
Equas Reference Laboratories
Marta Esteban
Karen Exley
Marc E Fisher
Margaretha Grander
Silvia Gómez
Philipp Hohenblum
Elly Den Hond
Milena Horvat
Beata Janasik
José A Jiménez-Guerrero
Anke Joas
Reinhard Joas
Kate Jones
Lucie Kašparová
Lisbeth E Knudsen
Holger M Koch
Marike Kolossa-Gehring
Thorjørn Larssen
Miklos Naray
Flemming Nielsen
Rui Pinto
Catherine Pirard
Gregory Plateel
Teresa C Rivas
Montserrat Rosado
Birgit K Schindler
Greet Schoeters
Ovnair Sepai
Janja Tratnik
Jürgen Wittsiepe
Publication date
1 August 2015
Publisher
'Elsevier BV'
Doi
Cite
Abstract
Human biomonitoring (HBM) is an effective tool for assessing actual exposure to chemicals that takes into account all routes of intake. Although hair analysis is considered to be an optimal biomarker for assessing mercury exposure, the lack of harmonization as regards sampling and analytical procedures has often limited the comparison of data at national and international level. The European-funded projects COPHES and DEMOCOPHES developed and tested a harmonized European approach to Human Biomonitoring in response to the European Environment and Health Action Plan. Herein we describe the quality assurance program (QAP) for assessing mercury levels in hair samples from more than 1800 mother-child pairs recruited in 17 European countries. To ensure the comparability of the results, standard operating procedures (SOPs) for sampling and for mercury analysis were drafted and distributed to participating laboratories. Training sessions were organized for field workers and four external quality-assessment exercises (ICI/EQUAS), followed by the corresponding web conferences, were organized between March 2011 and February 2012. ICI/EQUAS used native hair samples at two mercury concentration ranges (0.20-0.71 and 0.80-1.63) per exercise. The results revealed relative standard deviations of 7.87-13.55% and 4.04-11.31% for the low and high mercury concentration ranges, respectively. A total of 16 out of 18 participating laboratories the QAP requirements and were allowed to analyze samples from the DEMOCOPHES pilot study. Web conferences after each ICI/EQUAS revealed this to be a new and effective tool for improving analytical performance and increasing capacity building. The procedure developed and tested in COPHES/DEMOCOPHES would be optimal for application on a global scale as regards implementation of the Minamata Convention on Mercury.publisher: Elsevier articletitle: Mercury analysis in hair: Comparability and quality assessment within the transnational COPHES/DEMOCOPHES project journaltitle: Environmental Research articlelink: http://dx.doi.org/10.1016/j.envres.2014.11.014 content_type: article copyright: Copyright © 2014 Elsevier Inc. All rights reserved.status: publishe
Similar works
Full text
Available Versions
Lirias
See this paper in CORE
Go to the repository landing page
Download from data provider
oai:lirias2repo.kuleuven.be:12...
Last time updated on 10/12/2019