Many popular Bayesian nonparametric priors can be characterized in terms of
exchangeable species sampling sequences. However, in some applications,
exchangeability may not be appropriate. We introduce a {novel and
probabilistically coherent family of non-exchangeable species sampling
sequences characterized by a tractable predictive probability function with
weights driven by a sequence of independent Beta random variables. We compare
their theoretical clustering properties with those of the Dirichlet Process and
the two parameters Poisson-Dirichlet process. The proposed construction
provides a complete characterization of the joint process, differently from
existing work. We then propose the use of such process as prior distribution in
a hierarchical Bayes modeling framework, and we describe a Markov Chain Monte
Carlo sampler for posterior inference. We evaluate the performance of the prior
and the robustness of the resulting inference in a simulation study, providing
a comparison with popular Dirichlet Processes mixtures and Hidden Markov
Models. Finally, we develop an application to the detection of chromosomal
aberrations in breast cancer by leveraging array CGH data.Comment: For correspondence purposes, Edoardo M. Airoldi's email is
[email protected]; Federico Bassetti's email is
[email protected]; Michele Guindani's email is
[email protected] ; Fabrizo Leisen's email is
[email protected]. To appear in the Journal of the American
Statistical Associatio